HudsonAlpha Awarded 2025 AWS Imagine Grant to Advance Rare Disease Research

HudsonAlpha Institute for Biotechnology has been selected as a winner of the 2025 Amazon Web Services (AWS) Imagine Grant: Children’s Health Innovation Award, a grant designed to accelerate innovation in improving children’s health outcomes through advanced cloud services.

By focusing on children’s health, AWS seeks to bring more focus and attention to a wide variety of causes and care organizations that are dedicated to helping children live longer, healthier lives through the strategic use of cloud technology. The grant will support HudsonAlpha’s efforts to help clinicians and researchers better understand rare diseases that affect children and their families.

HudsonAlpha was named a recipient in the Children’s Health Innovation Award category, which recognizes highly innovative, mission-critical projects accelerating children’s health innovation using advanced cloud services. HudsonAlpha will receive a combination of funding and AWS computing credits, along with implementation support from technical specialists. Proposals were evaluated based on several criteria, including the innovative and unique nature of the project, impact on mission-critical goals, and clearly defined outcomes and milestones.

“This year’s AWS Children’s Health Innovation Award recipients are truly inspiring,” said Allyson Fryhoff, Managing Director, Global Healthcare and Life Sciences at AWS. “These leading pediatric institutions are using AWS technology to transform how we care for children worldwide. From using generative AI for personalized treatment decisions to creating predictive analytics for disease prevention, their projects share a powerful vision: making high-quality care more accessible, predictive, and effective for every child. At AWS, we’re proud to support this collaborative innovation that’s building a future where every child can access the best possible care, informed by data and delivered with precision and compassion.”

HudsonAlpha will use the grant to further develop its medical analysis tool to help healthcare professionals and researchers better understand rare diseases that affect children and their families. The system utilizes cloud technology and artificial intelligence to rapidly analyze patients’ genetic information, enabling a more accurate determination of the cause of a child’s rare disease and the identification of more effective treatment approaches. The tool is updated with the latest medical discoveries, allowing families to obtain answers about their children’s health conditions.

Since the launch of the Imagine Grant program in 2018, AWS has awarded more than $16 million in unrestricted funding, AWS cloud computing credits, and technical expertise to more than 140 nonprofit organizations. Learn more about past recipients and how nonprofits use AWS to advance their missions around the world at the AWS for nonprofits hub.